Food and medicine interaction

Ashwagandha and immunosuppressants, such as drugs taken after a transplant or for autoimmune disease

TheoreticalEvidence level: theoretical. Suggested by how the food and the drug work, or by lab data. Not shown in people.

Last reviewed

What can happen

NCCIH lists immunosuppressants among medicines ashwagandha might interact with and says it is not recommended for people with autoimmune disorders. Whether it changes how these drugs work is not known.

Why it happens
NCCIH lists the interaction without a mechanism, and it has not been studied in people taking these drugs.
At ordinary food amounts
Ashwagandha is taken as a supplement, not a food; any regular use counts.

What to do

If you take an immunosuppressant, do not start ashwagandha without your prescriber or transplant team approving it. Do not change your immunosuppressant on your own.

Never stop or change a prescribed medicine without talking to the prescriber.

Common questions

Can I have ashwagandha while taking immunosuppressants?

If you take an immunosuppressant, do not start ashwagandha without your prescriber or transplant team approving it. Do not change your immunosuppressant on your own. Ashwagandha is taken as a supplement, not a food; any regular use counts.

Sources

  1. National Center for Complementary and Integrative Health. Ashwagandha.
  2. NIH Office of Dietary Supplements. Ashwagandha: Fact Sheet for Health Professionals.

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