Remedy · root & spice

Valerian: what the evidence says about sleep

The best-known herbal sleep aid, with decades of mixed trials. People sometimes rate their sleep as better, but objective measures do not improve and sleep doctors advise against it for insomnia.

By the editors of Alimentotherapy Last reviewed 4 min read Not medical advice

Valerian

Valeriana officinalis

Best-supported use: Self-rated sleep quality

EvidenceLimitedbest use

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The short answer

The evidence on valerian for sleep is inconsistent: in pooled trials more people said their sleep improved, but time to fall asleep and sleep-quality scales did not change compared with placeboFernandez 2010; NCCIH. The American Academy of Sleep Medicine suggests clinicians not use valerian for chronic insomnia, so we grade self-rated sleep limited and measured sleep onset not supported Sateia 2017.

The evidence, use by use

Each claim graded on human studies only. How we grade

UseGradeWhat the research found
Self-rated sleep qualityLimitedAcross 18 trials, people on valerian were more likely to report improved sleep (relative risk 1.37), and an earlier review of 16 trials found a similar result with evidence of publication bias. Most trials had significant design problems. Fernandez 2010; Bent 2006
Time to fall asleep and insomnia severityNot supportedIn the 18-trial meta-analysis, time to fall asleep differed from placebo by 0.70 minutes and sleep-quality scale scores did not differ. A 14-trial review of herbal medicines for insomnia found no significant benefit on any of 13 measures. Fernandez 2010; Leach 2015; Sateia 2017
Anxiety and stressLimitedNCCIH says there is not enough evidence to draw conclusions about valerian for anxiety, stress or depression. NCCIH
Menopausal hot flashesLimitedThree small studies suggest valerian might help menopause symptoms, but NCCIH says there is not enough evidence to know for certain. NCCIH

What valerian is

Valerian is a plant native to Europe and Asia whose roots and underground stems have been used as medicine since ancient Greece and Rome. Today it is sold mainly for insomnia, anxiety and stressNCCIH. It is sold as dried root, tea, capsules of powder or extract, and tinctures, and trials have used a wide range of preparations and doses Bent 2006.

Sleep: why the results disagree

Valerian has been tested in many trials, and the reviews keep landing in the same place: a possible subjective benefit, no measurable one.

  • A 2006 review found 16 placebo-controlled trials with 1,093 patients. Most had significant methodological problems, and doses, preparations and treatment lengths varied widely. Six studies reporting whether sleep quality improved showed a benefit (relative risk 1.8), but with evidence of publication biasBent 2006.
  • A 2010 meta-analysis of 18 trials found the same subjective benefit (relative risk 1.37), but no difference in time to fall asleep (0.70 minutes) and no difference on sleep-quality scales. The authors concluded its effect has not been shown with quantitative or objective measures Fernandez 2010.
  • A 2015 review of 14 trials of herbal medicines in 1,602 people with insomnia, including valerian, found no significant difference from placebo on any of 13 efficacy measures, and more adverse events per person with valerian Leach 2015.
  • A 2020 review including 60 studies argued that inconsistent results may come from the variable quality of extracts, and that whole root may work more reliably Shinjyo 2020. That is a hypothesis, not a finding from head-to-head trials.

Putting this together, the American Academy of Sleep Medicine suggests that clinicians not use valerian for sleep-onset or sleep-maintenance insomnia in adults, a weak recommendation Sateia 2017, and NCCIH calls the sleep evidence inconsistent NCCIH.

For insomnia that lasts, our sleep page covers the approach guideline bodies put first, cognitive behavioral therapy for insomnia (CBT-I), along with caffeine and alcohol timing. For a gentler bedtime drink, see chamomile vs valerian.

Amounts used

NCCIH says valerian has been used with apparent safety at 300 to 600 mg a day for up to 6 weeks, and that its long-term safety is unknown NCCIH. The EU monograph lists 400 to 600 mg of dry extract as a single dose, or 0.3 to 3 g of the root for traditional use, taken half an hour to an hour before bed when used to aid sleep EMA.

If you want to try the root itself, iHerb lists dried valerian root and teas; check the label for the species and the amount per dose.

Side effects, alcohol and stopping

Reported side effects include headache, stomach upset, mental dullness, excitability, uneasiness and vivid dreams. Stopping suddenly after long use may cause withdrawal symptoms such as anxiety, irritability, heart disturbances and insomnia. Very rare cases of liver injury have been reported, mostly with valerian taken alongside other herbs NCCIH.

Safety

Do not combine valerian with alcohol or sedative medicines, and do not drive if it makes you drowsyNCCIH; EMA.

Before you try it: safety and interactions

Who should avoid it or ask first

  • You drink alcohol or take sedatives, sleeping pills or other drugs that cause drowsiness.
  • You need to drive or use machines and it makes you drowsy.
  • The person is a child under 12: safety and efficacy have not been established.
  • You have liver disease: ask your clinician first.

Possible side effects

  • Headache, stomach upset, mental dullness, excitability, uneasiness and vivid dreams.
  • Nausea and abdominal cramps.
  • Withdrawal symptoms if stopped suddenly after long use.
  • Very rare liver injury, mostly in combination with other herbs.

Pregnancy and breastfeeding

Little is known about valerian in pregnancy or breastfeeding, and the EU monograph does not recommend it during either. NCCIH; EMA

Common questions

Does valerian help you sleep?

The evidence is inconsistent. In a meta-analysis of 18 trials, more people on valerian said their sleep improved, but time to fall asleep differed from placebo by under a minute. The American Academy of Sleep Medicine suggests clinicians not use valerian for chronic insomnia.

How much valerian is safe?

NCCIH says 300 to 600 mg a day has been used with apparent safety for up to 6 weeks; long-term safety is unknown. Do not combine it with alcohol or sedatives, and avoid driving if it makes you drowsy.

Can you stop valerian suddenly?

After long use, NCCIH says stopping abruptly may cause withdrawal symptoms such as anxiety, irritability, heart disturbances and insomnia. If you have taken it nightly for a long time, ask your clinician about tapering.

Sources

Primary research and government sources, each checked on the date this page was reviewed.

  1. PubMedFernández-San-Martín MI, et al. Effectiveness of Valerian on insomnia: a meta-analysis of randomized placebo-controlled trials. Sleep Med. 2010. PMID 20347389.
  2. PubMedBent S, et al. Valerian for sleep: a systematic review and meta-analysis. Am J Med. 2006. PMID 17145239.
  3. PubMedLeach MJ, Page AT. Herbal medicine for insomnia: A systematic review and meta-analysis. Sleep Med Rev. 2015. PMID 25644982.
  4. PubMedShinjyo N, et al. Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis. J Evid Based Integr Med. 2020. PMID 33086877.
  5. GuidelineSateia MJ, et al. Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med. 2017. PMID 27998379.
  6. NCCIHNational Center for Complementary and Integrative Health. Valerian.
  7. GuidelineEuropean Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Valeriana officinalis L., radix. EMA/HMPC/150848/2015.

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