Food and medicine interaction

Milk, yogurt, cheese and calcium-fortified juice and tetracycline antibiotics and fluoroquinolones such as ciprofloxacin

EstablishedEvidence level: established. Shown in drug labeling or in controlled studies in people.

Last reviewed

What can happen

Calcium binds these antibiotics in the gut, so less of the drug is absorbed and the infection may be treated less well.

Why it happens
Calcium (and magnesium, iron and zinc) forms insoluble complexes with tetracyclines and fluoroquinolones.
At ordinary food amounts
Yes, ordinary servings matter. MedlinePlus says not to take tetracycline with dairy such as milk, yogurt, cheese and ice cream, and not to take ciprofloxacin with dairy products or calcium-fortified juices alone.

What to do

Follow the timing on your prescription label and ask your pharmacist how far apart to keep dairy and the antibiotic. Finish the course as prescribed.

Never stop or change a prescribed medicine without talking to the prescriber.

Common questions

Can I have milk, yogurt, cheese and calcium-fortified juice while taking antibiotics?

Follow the timing on your prescription label and ask your pharmacist how far apart to keep dairy and the antibiotic. Finish the course as prescribed. Yes, ordinary servings matter. MedlinePlus says not to take tetracycline with dairy such as milk, yogurt, cheese and ice cream, and not to take ciprofloxacin with dairy products or calcium-fortified juices alone.

Sources

  1. MedlinePlus (U.S. National Library of Medicine). Tetracycline: drug information.
  2. MedlinePlus (U.S. National Library of Medicine). Ciprofloxacin: drug information.

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