Side by side · Knee osteoarthritis pain

Turmeric vs ginger for joint pain: what the trials show

Both have been tested as supplements for osteoarthritis pain. Curcumin has more and larger trials; ginger's effect was small and more people stopped taking it. Neither is a reason to sprinkle more spice on dinner.

By the editors of Alimentotherapy Last reviewed 5 min read Not medical advice

Turmeric

For knee osteoarthritis pain: Moderate

Ginger

For knee osteoarthritis pain: Limited

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The short answer

For knee osteoarthritis pain, curcumin (the main active compound in turmeric) has moderate evidence: a meta-analysis of 11 trials in 1,258 people found it lowered pain scores more than comparators, with doses under 1,000 mg a day doing as well as higher ones Hsiao 2021. Ginger has limited evidence: five placebo-controlled trials (593 patients) showed a modest reduction in pain, and people taking ginger were more than twice as likely to stop Bartels 2015.

Side by side

Grades come from each remedy page and are based on human studies only. How we grade

 TurmericGinger
Best evidenceMeta-analysis of 11 trials, 1,258 people with knee OAMeta-analysis of 5 trials, 593 people with OA
What was testedCurcuminoid supplements, not turmeric in foodOral ginger supplements against placebo
AmountsUnder 1,000 mg a day did as well as moreVaried by trial
Size of effectLower pain scores than comparatorsModest reduction in pain and disability
Common side effectsNausea, reflux, stomach upset, diarrheaAbdominal discomfort, heartburn, diarrhea
Biggest drawbackRare liver injury, mostly with supplementsTwice as many people stopped it as stopped placebo
Avoid or ask firstLiver disease; blood thinners; pregnancy (supplements)Blood thinners; any regular medicine; surgery coming up
Kitchen formGround spice; too little curcumin to match trial dosesFresh or ground root; tea

Choose turmeric if

You want the option with more trial support for knee osteoarthritis pain, you have no liver problems, and you will choose a standard (not high-absorption) curcumin product with your clinician.

Choose ginger if

You already use ginger for nausea or like it as a tea, you accept a small effect at best, and you do not take a blood thinner.

Turmeric and curcumin: more trials, still modest

The joint-pain trials tested curcuminoids, the concentrated compounds extracted from turmeric root, not the spice in a curry. A 2021 meta-analysis pooled 11 randomized trials with 1,258 people who had knee osteoarthritis. Curcuminoids lowered pain scores more than the comparators, which included placebo and, in some trials, non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen. High doses (1,000 mg a day or more) did no better than low doses, and side effects did not differ between them. In the three trials that used NSAIDs as the comparison, all reported more side effects with the NSAID Hsiao 2021.

NCCIH describes the osteoarthritis evidence as initially positive but says higher-quality evidence is needed before firm conclusions, and more work is needed on how absorption affects the resultsNCCIH. That is why this site grades it moderate, not strong.

Curcumin is poorly absorbed on its own. In volunteers given 2 g of curcumin alone, blood levels were undetectable or very low; adding 20 mg of piperine, from black pepper, raised absorption sharplyShoba 1998. Higher absorption has a cost, covered under safety below.

Ginger: a small effect, and more people stop

The best summary for ginger is a 2015 meta-analysis of five placebo-controlled trials in 593 adults with osteoarthritis. Ginger produced a statistically significant but small reduction in pain and in disability. Withdrawals because of side effects were more than twice as common with ginger as with placebo. The reviewers judged the evidence moderate quality, limited by small numbers, and called ginger modestly effective and reasonably safe Bartels 2015.

NCCIH says ginger supplements might help knee osteoarthritis symptoms, but much of the research has been of poor quality, and ginger applied to the skin has not been shown to help NCCIH. With few trials and a small effect, ginger is graded limited for joint pain here. Its better-supported use is nausea; see ginger vs peppermint for nausea.

Neither has been tested against the other

We found no trial that put turmeric and ginger head to head for joint pain, so the comparison on this page rests on how each did against placebo or other treatments. Curcumin has about twice as many trial participants behind it, and its effect held up across doses. Ginger's trials are fewer and its effect smaller. Some supplements combine the two; a trial of a combination cannot tell you which ingredient did what.

In the kitchen

Cooking with either spice is pleasant and safe, but no trial shows a joint effect from food amounts of turmeric NCCIH. A mug of golden milk or ginger tea is a fine habit; it is not the dose the trials used.

Neither spice replaces the usual osteoarthritis care a clinician can walk you through. Severe, unexplained or lasting joint pain and swelling needs a diagnosis first; the inflammation page covers when to get help.

Safety: the liver for turmeric, the stomach for ginger

Turmeric. NCCIH says standard oral turmeric or curcumin is likely safe in recommended amounts for up to 2 or 3 months, and can cause nausea, vomiting, acid reflux, stomach upset, diarrhea or constipation. Liver damage has been reported with high-absorption curcumin products. Stop and call your clinician if you notice fatigue, nausea, poor appetite, dark urine or yellowing skin or eyes. Turmeric supplements may be unsafe in pregnancy NCCIH. The US Drug-Induced Liver Injury Network described 10 cases of turmeric-associated liver injury, all since 2011; five people were hospitalized and one died, and three of the seven products tested also contained black pepper extractHalegoua 2023.

Ginger. NCCIH lists abdominal discomfort, heartburn, diarrhea, and mouth and throat irritation as side effects, and advises talking with your clinician first if you take any medicineNCCIH. In the osteoarthritis trials, stopping because of side effects was the main drawback Bartels 2015.

Both are flagged for people on blood thinners. Read turmeric and anticoagulants and ginger and anticoagulants before taking either as a supplement, and tell your surgical team about them before any operation.

If you decide to try one, the spice or tea is easy to find; online, iHerb turmeric powder and iHerb ginger tea list single-ingredient options.

Common questions

Is turmeric or ginger better for arthritis pain?

Turmeric's curcumin has more trial support. A 2021 meta-analysis of 11 trials in 1,258 people with knee osteoarthritis found curcuminoids lowered pain scores, while a 2015 meta-analysis of 5 ginger trials (593 patients) found only a modest effect, with more people stopping ginger. They have not been tested against each other.

How much curcumin was used for knee pain?

Doses varied, but the 2021 meta-analysis found daily doses under 1,000 mg relieved pain as well as higher doses, with similar side effects. NCCIH warns that high-absorption curcumin products have been linked to liver damage.

Does cooking with turmeric help joint pain?

There is no trial evidence that it does. The trials used concentrated curcumin supplements, and in volunteers given 2 g of curcumin alone, blood levels were undetectable or very low. Cooking with turmeric is safe, but it is not the trial dose.

Sources

Primary research and government sources, each checked on the date this page was reviewed.

  1. PubMedHsiao AF, et al. The efficacy of high- and low-dose curcumin in knee osteoarthritis: a systematic review and meta-analysis. Complement Ther Med. 2021. PMID 34537344.
  2. PubMedBartels EM, et al. Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials. Osteoarthritis Cartilage. 2015. PMID 25300574.
  3. PubMedShoba G, et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998. PMID 9619120.
  4. PubMedHalegoua-DeMarzio D, et al. Liver injury associated with turmeric: a growing problem. Ten cases from the Drug-Induced Liver Injury Network [DILIN]. Am J Med. 2023. PMID 36252717.
  5. NCCIHNational Center for Complementary and Integrative Health. Turmeric: Usefulness and Safety.
  6. NCCIHNational Center for Complementary and Integrative Health. Ginger: Usefulness and Safety.

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